Good manufacturing practice production of human corneal limbus-derived stromal stem cells and in vitro quality screening for therapeutic inhibition of corneal scarring

Abstract Background Mesenchymal stem cells in the adult corneal stroma (named corneal stromal stem cells, CSSCs) inhibit corneal inflammation and scarring and restore corneal clarity in pre-clinical corneal injury models. This cell therapy could alleviate the heavy reliance on donor materials for co...

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Главные авторы:	Mithun Santra, Moira L. Geary, Elizabeth Rubin, Michael Y. S. Hsu, Martha L. Funderburgh, Christine Chandran, Yiqin Du, Deepinder K. Dhaliwal, Vishal Jhanji, Gary Hin-Fai Yam
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2024-01-01
Серии:	Stem Cell Research & Therapy
Предметы:	Cornea scarring Cell therapy Corneal stromal stem cells Good manufacturing practice Quality control
Online-ссылка:	https://doi.org/10.1186/s13287-023-03626-8
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