<i>Notch</i> Missense Mutations in <i>Drosophila</i> Reveal Functions of Specific EGF-like Repeats in Notch Folding, Trafficking, and Signaling

Notch signaling plays various roles in cell-fate specification through direct cell–cell interactions. Notch receptors are evolutionarily conserved transmembrane proteins with multiple epidermal growth factor (EGF)-like repeats. <i>Drosophila</i> Notch has 36 EGF-like repeats, and while some play a r...

Full beskrivning

Bibliografiska uppgifter

Huvudupphov:	Hilman Nurmahdi, Mao Hasegawa, Elzava Yuslimatin Mujizah, Takeshi Sasamura, Mikiko Inaki, Shinya Yamamoto, Tomoko Yamakawa, Kenji Matsuno
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2022-11-01
Serie:	Biomolecules
Ämnen:	Notch Notch signaling pathway lateral inhibition asymmetric cell division protein folding intracellular trafficking
Länkar:	https://www.mdpi.com/2218-273X/12/12/1752
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!