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Reactive spinal glia convert 2-AG to prostaglandins to drive aberrant astroglial calcium signaling

The endogenous cannabinoid 2-arachidonoylglycerol (2-AG) influences neurotransmission in the central nervous system mainly by activating type 1 cannabinoid receptor (CB1). Following its release, 2-AG is broken down by hydrolases to yield arachidonic acid, which may subsequently be metabolized by cyc...

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Bibliografische gegevens
Hoofdauteurs: Klaudia Dócs, Anita Balázs, Ildikó Papp, Peter Szücs, Zoltán Hegyi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2024-05-01
Reeks:Frontiers in Cellular Neuroscience
Onderwerpen:
Online toegang:https://www.frontiersin.org/articles/10.3389/fncel.2024.1382465/full
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