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Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO

MARCO is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). Previously, it was shown that mice null for MARCO have a greater inflammatory response to silica, but the mechanism was not described. The aim of this study was to determine the...

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Bibliografische gegevens
Hoofdauteurs: Rupa Biswas, Raymond F. Hamilton, Andrij Holian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley 2014-01-01
Reeks:Journal of Immunology Research
Online toegang:http://dx.doi.org/10.1155/2014/304180
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