Promoter regulatory mode evolution enhances the high multidrug resistance of tmexCD1-toprJ1

ABSTRACTAntibiotic resistance could rapidly emerge from acquiring the mobile antibiotic resistance genes, which are commonly evolved from an intrinsic gene. The emergence of the plasmid-borne mobilized efflux pump gene cluster tmexCD1-toprJ1 renders the last-resort antibiotic tigecycline ineffective...

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Detalhes bibliográficos

Principais autores:	Chengzhen Wang, Jun Yang, Zeling Xu, Luchao Lv, Sheng Chen, Mei Hong, Jian-Hua Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2024-05-01
coleção:	mBio
Assuntos:	antibiotic resistance tigecycline gene regulation evolution tmexCD-toprJ
Acesso em linha:	https://journals.asm.org/doi/10.1128/mbio.00218-24
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