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Identification and Characterization of Carboxylesterases from Brachypodium distachyon Deacetylating Trichothecene Mycotoxins

Increasing frequencies of 3-acetyl-deoxynivalenol (3-ADON)-producing strains of Fusarium graminearum (3-ADON chemotype) have been reported in North America and Asia. 3-ADON is nearly nontoxic at the level of the ribosomal target and has to be deacetylated to cause inhibition of protein biosynthesis....

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Principais autores: Clemens Schmeitzl, Elisabeth Varga, Benedikt Warth, Karl G. Kugler, Alexandra Malachová, Herbert Michlmayr, Gerlinde Wiesenberger, Klaus F. X. Mayer, Hans-Werner Mewes, Rudolf Krska, Rainer Schuhmacher, Franz Berthiller, Gerhard Adam
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2015-12-01
Serier:Toxins
Fag:
Fusarium graminearum
trichothecene metabolism
3-acetyl-deoxynivalenol
15-acetyl-deoxynivalenol
monocot
enzymatic cleavage
Online adgang:http://www.mdpi.com/2072-6651/8/1/6
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