Interaction between Parkin and <i>α</i>-Synuclein in <i>PARK2</i>-Mediated Parkinson’s Disease

Parkin and <i>α</i>-synuclein are two key proteins involved in the pathophysiology of Parkinson’s disease (PD). Neurotoxic alterations of <i>α</i>-synuclein that lead to the formation of toxic oligomers and fibrils contribute to PD through synaptic dysfunction, mitochondrial impairment, defective en...

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Bibliografski detalji

Glavni autori:	Daniel Aghaie Madsen, Sissel Ida Schmidt, Morten Blaabjerg, Morten Meyer
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-01-01
Serija:	Cells
Teme:	familial Parkinson’s disease <i>PARK2</i> parkin <i>α</i>-synuclein Lewy bodies
Online pristup:	https://www.mdpi.com/2073-4409/10/2/283
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