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Ultrasound‐targeted microbubble destruction mediates PDE5i/NO integration for cavernosum remodeling and penile rehabilitation

Abstract Erectile dysfunction (ED) caused by cavernous nerve injury (CNI) is refractory to heal mainly ascribed to the adverse remodeling of the penis induced by ineffectual microvascular perfusion, fibrosis, and neurotrophins scarcity in cavernosum. Phosphodiesterase type V inhibitors (PDE5i) have...

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Principais autores: Wende Yang, Chen Qiu, Jiancheng Zhai, Wei Zhang, Chengwu Huang, Jun Shao, Jingke Zhang, Shigao Chen, Xiaoyan Miao, Peng Chen, Bo Wei, Jie Ren, Hongbo Wei
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2023-09-01
Serija:Bioengineering & Translational Medicine
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Online dostop:https://doi.org/10.1002/btm2.10568
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