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5-hydroxyeicosatetraenoic acid and 12-hydroxyeicosapentaenoic acid regulate basophil and mast cell activation and basophil recruitment in chronic spontaneous urticaria

Background: The underlying pathomechanisms of wheal reaction enlargement in chronic spontaneous urticaria (CSU) remain largely unclear. We hypothesized that the activation of mast cells (MCs) and recruitment of basophils to locally inflamed skin would be enhanced by lipid mediators (LMs) following i...

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主要な著者: Mana Ito, Yoshimi Miki, Shota Toyoshima, Maho Tagui, Koremasa Hayama, Hideki Fujita, Yoshitaka Taketomi, Makoto Murakami, Yoshimichi Okayama
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2026-07-01
シリーズ:Allergology International
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S1323893025001534
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