Modulation of APC function and anti-tumor immunity by anti-cancer drugs

Professional antigen-presenting cells, such as dendritic cells are central to the initiation and regulation of anti-cancer immunity. However, in the immunosuppressive environment within a tumor APCs may antagonize anti-tumor immunity by inducing regulatory T cells (Tregs) or anergy of effector T cel...

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Detalles Bibliográficos

Principais autores:	Kea eMartin, Jens eSchreiner, Alfred eZippelius
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2015-09-01
Series:	Frontiers in Immunology
Assuntos:	Dendritic Cells chemotherapy Immunogenic cell death anti-tumor immunity antigen-presenting cell tumor-induced T cell dysfunction
Acceso en liña:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00501/full
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