Polyenes in Medium Chain Length Polyhydroxyalkanoate (mcl-PHA) Biopolymer Microspheres with Reduced Toxicity and Improved Therapeutic Effect against <i>Candida</i> Infection in Zebrafish Model

Immobilizing antifungal polyenes such as nystatin (Nys) and amphotericin B (AmB) into biodegradable formulations is advantageous compared to free drug administration providing sustained release, reduced dosing due to localized targeting and overall reduced systemic drug toxicity. In this study, we e...

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Hlavní autoři:	Aleksandar Pavic, Zoran Stojanovic, Marina Pekmezovic, Đorđe Veljović, Kevin O’Connor, Ivana Malagurski, Jasmina Nikodinovic-Runic
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-03-01
Edice:	Pharmaceutics
Témata:	polyene polyhydroxyalkanoate PHA formulation microsphere <i>Candida albicans</i>
On-line přístup:	https://www.mdpi.com/1999-4923/14/4/696
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