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Antibacterial and cytotoxic effects of chlorhexidine combined with sodium DNA on oral microorganisms: an in vitro study using Dictyostelium discoideum

Background Chlorhexidine (CHX) is widely used in oral care for its broad-spectrum antimicrobial activity but can cause significant side effects. Sodium DNA has emerged as a potential adjunct capable of modulating cellular responses.Aim This study assessed whether sodium DNA enhances the antibacteria...

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Principais autores: Simone Rocco, Adriana Antonina Tempesta, Gaia Vertillo Aluisio, Maria Lina Mezzatesta, Alessandra Romano, Valentina Schiavo, Barbara Pergolizzi, Maria Santagati*, Cristina Panuzzo, Gaetano Isola
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2025-12-01
Serier:Journal of Oral Microbiology
Fag:
Mouthwashes
chlorhexidine
sodium DNA
oral bacteria
Dictyostelium discoideum
phagocytosis
Online adgang:https://www.tandfonline.com/doi/10.1080/20002297.2025.2595797
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