Nanotechnological synergy of mangiferin and curcumin in modulating PI3K/Akt/mTOR pathway: a novel front in ovarian cancer precision therapeutics

Background: Ovarian cancer, colloquially termed the “silent killer” among gynecological malignancies, remains elusive due to its often-asymptomatic progression and diagnostic challenges. Central to its pathogenesis is the overactive PI3K/Akt/mTOR signaling pathway, responsible for various cellular f...

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Principais autores:	Hanan M. Alharbi, Taha Alqahtani, Ali H. Alamri, Vinoth Kumarasamy, Vetriselvan Subramaniyan, K. Suresh Babu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-01-01
coleção:	Frontiers in Pharmacology
Assuntos:	ovarian cancer therapeutics therapeutic efficacy mangiferin curcumin PI3K/Akt/mTOR pathway synergistic interplay
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1276209/full
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