Engineering of Stimulus-Responsive Pirfenidone Liposomes for Pulmonary Delivery During Treatment of Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by progressive and irreversible loss of lung function. Clinically safe and efficacious drug treatments for IPF are lacking. Pirfenidone (an anti-inflammatory, antioxidant and anti-fibrotic small-molecule drug) is consi...

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Principais autores:	Meishan Han, Yingjian Song, Sha Liu, Xiaoyan Lu, Linyu Su, Meixuan Liu, Xiaosu Zhu, Kaoxiang Sun, Yanan Lu, Aiping Wang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2022-04-01
Series:	Frontiers in Pharmacology
Assuntos:	pirfenidone idiopathic pulmonary fibrosis stimulus-responsive liposomes pulmonary administration permeability of the mucus layer
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fphar.2022.882678/full
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