GABA/baclofen stabilizes PD-L1 and enhances immunotherapy of breast cancer
The programmed death-ligand 1 (PD-L1) on the surface of tumor cells binds to the receptor programmed cell death protein 1 (PD-1) on effector T cells, thereby inhibiting the anti-tumor immune response. Immune checkpoint blockade (ICB) therapy targeting PD-1/PD-L1 has been approved for the treatment o...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2024-04-01
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| Serier: | Heliyon |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S2405844024046310 |
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