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Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences

Lactoferrin (Lf) is a cationic glycoprotein synthetized by exocrine glands and is present in all human secretions. It is also secreted by neutrophils in infection and inflammation sites. This glycoprotein possesses antimicrobial activity due to its capability to chelate two ferric ions per molecule,...

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Hlavní autoři: Elena Campione, Caterina Lanna, Terenzio Cosio, Luigi Rosa, Maria Pia Conte, Federico Iacovelli, Alice Romeo, Mattia Falconi, Claudia Del Vecchio, Elisa Franchin, Maria Stella Lia, Marilena Minieri, Carlo Chiaramonte, Marco Ciotti, Marzia Nuccetelli, Alessandro Terrinoni, Ilaria Iannuzzi, Luca Coppeda, Andrea Magrini, Sergio Bernardini, Stefano Sabatini, Felice Rosapepe, Pier Luigi Bartoletti, Nicola Moricca, Andrea Di Lorenzo, Massimo Andreoni, Loredana Sarmati, Alessandro Miani, Prisco Piscitelli, Piera Valenti, Luca Bianchi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-06-01
Edice:Frontiers in Pharmacology
Témata:
lactoferrin
COVID-19
SARS-CoV-2
spike
bovine lactoferrin
On-line přístup:https://www.frontiersin.org/articles/10.3389/fphar.2021.666600/full
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