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Stromal Metalloproteinase-9 Is Essential to Angiogenesis and Progressive Growth of Orthotopic Human Pancreatic Cancer in Parabiont Nude Mice

We determined whether host matrix metalloproteinase (MMP) 9 is essential to angiogenesis and to the growth of L3.6pl human pancreatic cancer cells implanted into the pancreas of wild-type (MMP−9+/+) and knockout (MMP−9−/−) nude mice. Four weeks after tumor cell injection, pancreatic tumors in MMP−9+...

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Bibliografiska uppgifter
Huvudupphov: Toru Nakamura, Toshio Kuwai, Jang-Seong Kim, Dominic Fan, Sun-Jin Kim, Isaiah J. Fidler
Materialtyp: Artigo
Språk:Inglês
Utgiven: Elsevier 2007-11-01
Serie:Neoplasia: An International Journal for Oncology Research
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Länkar:http://www.sciencedirect.com/science/article/pii/S1476558607800261
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