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Promotive role of IRF7 in ferroptosis of colonic epithelial cells in ulcerative colitis by the miR-375-3p/SLC11A2 axis

Ferroptosis is implicated in the progression of ulcerative colitis (UC), and interferon regulatory factor 7 (IRF7) contributes to cell death. This study probed the mechanism of IRF7 in ferroptosis of colonic epithelial cells (ECs) in mice with dextran sodium sulfate (DSS)-induced UC. The UC mouse mo...

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Principais autores: Zepeng Chen, Qinglong Gu, Ruichao Chen
Format: Artigo
Sprog:Inglês
Udgivet: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023-05-01
Serier:Biomolecules & Biomedicine
Fag:
Ulcerative colitis
ferroptosis
IRF7
SLC11A2
miR-375-3p
GPX4
Online adgang:https://www.bjbms.org/ojs/index.php/bjbms/article/view/8081
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