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Proximity ligation assay to study protein–protein interactions of proteins on two different cells

Protein–protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently developed method, the proximity ligation assay (PLA...

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Bibliografiske detaljer
Principais autores: Rushikesh Sable, Nithya Jambunathan, Sitanshu Singh, Sandeep Pallerla, Konstantin G Kousoulas, Seetharama Jois
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2018-09-01
Serier:BioTechniques
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Online adgang:https://www.future-science.com/doi/10.2144/btn-2018-0049
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