Human brain cell types shape host-rabies virus transcriptional interactions revealing a preexisting pro-viral astrocyte subpopulation

Summary: How virus-host cell interactions and innate immune antagonism shape neurotropic infection dynamics across diverse brain cell types is largely unknown. To “unmask” and study how innate immune inhibition affects cell-type-specific transcriptional regulation of the human and viral genome, we p...

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Autori principali:	Lena Feige, Karl Young, Juan Pablo Cerapio, Tatsuya Kozaki, Lauriane Kergoat, Valentina Libri, Florent Ginhoux, Milena Hasan, Lamya Ben Ameur, Gregory Chin, Zach Goode, Hervé Bourhy, Arpiar Saunders
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-09-01
Serie:	Cell Reports
Soggetti:	CP: Neuroscience CP: Immunology
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124725009301
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