The multidimensional biology of SKP2: mechanisms, pathologies, and emerging therapeutic frontiers
S phase kinase-associated protein 2 (SKP2), the rate-limiting substrate receptor of the SKP1-Cullin1-F-box (SCF) E3 ubiquitin ligase complex, is considered a canonical gatekeeper of cell cycle progression. However, accumulating evidence indicates that SKP2 functions as a multifaceted signaling hub t...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Compuscript Ltd
2026-04-01
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| coleção: | Acta Materia Medica |
| Assuntos: | |
| Acesso em linha: | https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2025-0094 |
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