Serum titin/creatinine ratio as a biomarker for discriminating disease severity in Duchenne and Becker muscular dystrophies

IntroductionDuchenne/Becker muscular dystrophies (DMD/BMD) are inherited muscle diseases, collectively referred to as dystrophinopathy, which are characterized by progressive degeneration or loss. Although serum creatine kinase (CK) is a classical biomarker of DMD and BMD, it alone cannot clearly di...

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Principais autores:	Yoshinori Nambu, Kayo Osawa, Taku Shirakawa, Aiko Sunami, Shoko Sonehara, Ryosuke Bo, Kandai Nozu, Masafumi Matsuo, Hiroyuki Awano
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Neurology
Assuntos:	Duchenne muscular dystrophy Becker muscular dystrophy serum titin serum creatine kinase biomarker
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fneur.2025.1591748/full
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