Efficient Modulation of Exon Skipping via Antisense Circular RNAs
Splice-switching antisense oligonucleotides (ASOs) and engineered U7 small nuclear ribonucleoprotein (U7 Sm OPT) are the most commonly used methods for exon skipping. However, challenges remain, such as limited organ delivery and repeated dosing for ASOs and unknown risks of by-products produced by...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Association for the Advancement of Science (AAAS)
2023-01-01
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| Series: | Research |
| Acceso en liña: | https://spj.science.org/doi/10.34133/research.0045 |
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