The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses.

Infection with Citrobacter rodentium triggers robust tissue damage repair responses, manifested by secretion of IL-22, in the absence of which mice succumbed to the infection. Of the main hallmarks of C. rodentium infection are colonic crypt hyperplasia (CCH) and dysbiosis. In order to colonize the...

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Egile Nagusiak:	Cedric N Berger, Valerie F Crepin, Theodoros I Roumeliotis, James C Wright, Nicolas Serafini, Meirav Pevsner-Fischer, Lu Yu, Eran Elinav, James P Di Santo, Jyoti S Choudhary, Gad Frankel
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Public Library of Science (PLoS) 2018-10-01
Saila:	PLoS Pathogens
Sarrera elektronikoa:	https://doi.org/10.1371/journal.ppat.1007406
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