Theoretical Analysis of the Built-in Metabolic Pathway Effect on the Metabolism of Erythrocyte-Bioreactors That Neutralize Ammonium

The limitations of the efficiency of ammonium-neutralizing erythrocyte-bioreactors based on glutamate dehydrogenase and alanine aminotransferase reactions were analyzed using a mathematical model. At low pyruvate concentrations in the external medium (below about 0.3 mM), the main limiting factor is...

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Detalhes bibliográficos

Principais autores:	Evgeniy Protasov, Larisa Koleva, Elizaveta Bovt, Fazoil I. Ataullakhanov, Elena Sinauridze
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-01-01
coleção:	Metabolites
Assuntos:	ammonium removal erythrocyte erythrocyte-bioreactor limitations of the erythrocyte-bioreactor efficiency mathematical modeling
Acesso em linha:	https://www.mdpi.com/2218-1989/11/1/36
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