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Loss of stimulator of interferon genes (STING) promotes accumulation of cholesterol and triglycerides throughout life in mice

Abstract Background The Stimulator of Interferon Genes (STING) pathway is pivotal in innate immunity, facilitating the detection of cytosolic DNA and initiating type I interferon-dependent responses. In addition to its immunological roles, STING has been increasingly associated with metabolic regula...

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Hlavní autoři: Ian Riquelme, Daniela Carrillanca, Camila Sánchez-Pérez, Andrea Monterroza, Bairon Hernández-Rojas, Gonzalo Riadi, Gonzalo I. Cancino, Paola Murgas
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-07-01
Edice:Biological Research
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On-line přístup:https://doi.org/10.1186/s40659-025-00624-3
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