Atomistic fingerprint of hyaluronan-CD44 binding.
Hyaluronan is a polyanionic, megadalton-scale polysaccharide, which initiates cell signaling by interacting with several receptor proteins including CD44 involved in cell-cell interactions and cell adhesion. Previous studies of the CD44 hyaluronan binding domain have identified multiple widespread r...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2017-07-01
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| Schriftenreihe: | PLoS Computational Biology |
| Online-Zugang: | https://doi.org/10.1371/journal.pcbi.1005663 |
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