ATP2C2–PLA2R1 axis underlies lipid metabolism modulation and invasion in papillary thyroid carcinoma mediated by a VGIC signature

Abstract Objective Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with rising incidence globally. Current prognostic markers often lack precision for individualized management. This study develops a prognostic signature based on voltage-gated ion channel (VGIC) genes and ex...

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Autori principali:	Linlin Sun, Zhenxuan Sun, Wei Gao, Yinan Cao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2026-03-01
Serie:	Discover Oncology
Soggetti:	Papillary thyroid carcinoma Voltage-gated ion channels Prognostic signature Metabolic microenvironment
Accesso online:	https://doi.org/10.1007/s12672-026-04861-0
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