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Single-cell transcriptome dynamics of the autotaxin-lysophosphatidic acid axis during muscle regeneration reveal proliferative effects in mesenchymal fibro-adipogenic progenitors

Lysophosphatidic acid is a growth factor-like bioactive phospholipid recognising LPA receptors and mediating signalling pathways that regulate embryonic development, wound healing, carcinogenesis, and fibrosis, via effects on cell migration, proliferation and differentiation. Extracellular LPA is ge...

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Bibliografische gegevens
Hoofdauteurs: Osvaldo Contreras, Richard P. Harvey
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2023-02-01
Reeks:Frontiers in Cell and Developmental Biology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fcell.2023.1017660/full
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