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Acute Intestinal Inflammation Depletes/Recruits Histamine-Expressing Myeloid Cells From the Bone Marrow Leading to Exhaustion of MB-HSCsSummary

Background & Aims: Histidine decarboxylase (HDC), the histamine-synthesizing enzyme, is expressed in a subset of myeloid cells but also marks quiescent myeloid-biased hematopoietic stem cells (MB-HSCs) that are activated upon myeloid demand injury. However, the role of MB-HSCs in dextran sulfate...

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Asıl Yazarlar: Na Fu, Feijing Wu, Zhengyu Jiang, Woosook Kim, Tuo Ruan, Ermanno Malagola, Yosuke Ochiai, Osmel Companioni Nápoles, Giovanni Valenti, Ruth A. White, Bryana R. Belin, Leah B. Zamechek, Jonathan S. LaBella, Timothy C. Wang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2021-01-01
Seri Bilgileri:Cellular and Molecular Gastroenterology and Hepatology
Konular:
Histidine Decarboxylase (HDC)
Hematopoietic Stem Cell (HSC)
Myeloid Cell
Intestine Inflammation
H2-Receptor (H2R) Agonist
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2352345X20301867
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