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VEZF1 inhibits ovarian cancer cell ferroptosis and acts as an oncogene via the miR-545-3p/PLAG1 axis

Abstract Background Ovarian cancer (OC) is a fatal carcinoma for women. This study attempts to explore the role of vascular endothelial zinc finger 1 (VEZF1) in OC cell ferroptosis, thereby finding a new target for OC treatment. Methods Expressions of VEZF1, miR-545-3p and PLAG1 in HOSE cell line an...

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Main Authors: Wei Shi, Weiwei Feng, Jing Wan, Xiao-Ping Wan
Format: Artigo
Language:Inglês
Published: BMC 2026-04-01
Series:Hereditas
Subjects:
Ovarian cancer
High glucose
Ferroptosis
VEZF1
miR-545-3p
PLAG1
Online Access:https://doi.org/10.1186/s41065-026-00672-z
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