Lanifibranor Reduces Inflammation and Improves Dyslipidemia in Lysosomal Acid Lipase-Deficient Mice

Background and Aims: Recent studies showed that patients suffering from lysosomal acid lipase deficiency (LAL-D) benefit from enzyme replacement therapy; however, liver histopathology improved in some but not all patients. We hypothesized that the pan-peroxisome proliferator-activated receptor agoni...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Ivan Bradić, Nemanja Vujić, Katharina B. Kuentzel, Hansjörg Habisch, Anita Pirchheim, Alena Akhmetshina, John D. Henderson, Tobias Madl, Atul S. Deshmukh, Dagmar Kratky
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2024-01-01
Sarja:	Gastro Hep Advances
Aiheet:	LAL Lysosomal Acid Lipase Deficiency Liver Inflammation Lipoproteins Pan-PPAR Agonist
Linkit:	http://www.sciencedirect.com/science/article/pii/S2772572324000736
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