ATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation[S]

Neutral sphingomyelinase-2 (nSMase2) is a key ceramide-producing enzyme in cellular stress responses. While many posttranslational regulators of nSMase2 are known, emerging evidence suggests a more protracted regulation of nSMase2 at the transcriptional level. Previously, we reported that nSMase2 is...

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Үндсэн зохиолчид:	Christopher J. Clarke, Achraf A. Shamseddine, Joseph J. Jacob, Gabrielle Khalife, Tara A. Burns, Yusuf A. Hannun
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2016-05-01
Цуврал:	Journal of Lipid Research
Нөхцлүүд:	sphingolipids retinoids nuclear receptors transcription signal transduction histone deacetylase
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0022227520309895
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!