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Treatment effect modification due to comorbidity: Individual participant data meta-analyses of 120 randomised controlled trials

<h4>Background</h4> People with comorbidities are underrepresented in clinical trials. Empirical estimates of treatment effect modification by comorbidity are lacking, leading to uncertainty in treatment recommendations. We aimed to produce estimates of treatment effect modification by comorbidity u...

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Bibliografiska uppgifter
Huvudupphov: Peter Hanlon, Elaine W. Butterly, Anoop SV Shah, Laurie J. Hannigan, Jim Lewsey, Frances S. Mair, David M. Kent, Bruce Guthrie, Sarah H. Wild, Nicky J. Welton, Sofia Dias, David A. McAllister
Materialtyp: Artigo
Språk:Inglês
Utgiven: Public Library of Science (PLoS) 2023-06-01
Serie:PLoS Medicine
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243630/?tool=EBI
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