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Disulfide Bond Mapping of Follitropin Delta, a Recombinant Follicle Stimulating Hormone (rFSH), by X-Ray Crystallography

<b>Background/Objectives:</b> Follitropin delta is an approved recombinant follicle-stimulating hormone (rFSH) expressed in a human cell line. Correct disulfide connectivity is a critical quality attribute for rFSH, a heterodimeric glycoprotein composed of noncovalently associated α and β subunits a...

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Bibliographic Details
Main Authors: Dorin Kalson, Jeremiah S. Joseph, Hila Nudelman, Eyal Kamhi, Shlomo Bakshi
Format: Artigo
Language:Inglês
Published: MDPI AG 2026-02-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/19/3/380
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