Systemic Drivers and Molecular Mechanisms of Sarcopenia in Aetiology‐Specific End‐Stage Liver Disease

ABSTRACT Background Patients with end‐stage liver disease (ESLD) often present with sarcopenia, defined as loss of skeletal muscle mass and quality, which is associated with reduced quality of life and increased mortality. However, the molecular mechanisms driving sarcopenia in ESLD are not fully un...

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Autors principals:	Thomas Nicholson, Sophie L. Allen, Jonathan I. Quinlan, Amritpal Dhaliwal, Michael Macleod, Joshua Price, Jon Hazeldine, Michael S. Sagmeister, Caitlin Ditchfield, Kirsty C. McGee, Felicity R. Williams, Ahmed M. Elsharkawy, Matthew J. Armstrong, Carolyn A. Greig, Janet M. Lord, Leigh Breen, Simon W. Jones
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2026-06-01
Col·lecció:	Journal of Cachexia, Sarcopenia and Muscle
Matèries:	cytokines end‐stage liver disease human myotubes sarcopenia skeletal muscle
Accés en línia:	https://doi.org/10.1002/jcsm.70294
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