Generation of an isogenic CRISPR/Cas9-corrected control induced pluripotent stem cell line from a patient with autosomal dominant catecholaminergic polymorphic ventricular tachycardia with a heterozygous variant in cardiac calsequestrin-2

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac disease characterised by adrenergic-induced arrhythmias. The leading causes of CPVT are pathogenic variants in cardiac ryanodine receptor 2 (RYR2) and rarely, in cardiac calsequestrin-2 (CASQ2) genes, which are majo...

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Autores principales:	Ginell N. Ranpura, Mira Holliday, Serena Li, Samantha B. Ross, Emma S. Singer, Stuart T. Fraser, Richard D. Bagnall, Christopher Semsarian, Seakcheng Lim
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2025-03-01
Colección:	Stem Cell Research
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S1873506124003489
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