Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis

Abstract Fibroblasts play critical roles in tissue homeostasis, but in pathologic states they can drive fibrosis, inflammation, and tissue destruction. Little is known about what regulates the homeostatic functions of fibroblasts. Here, we perform RNA sequencing and identify a gene expression progra...

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Principais autores:	Heather J. Faust, Tan-Yun Cheng, Ilya Korsunsky, Gerald F. M. Watts, Shani T. Gal-Oz, William V. Trim, Suppawat Kongthong, Anna Helena Jonsson, Daimon P. Simmons, Fan Zhang, Robert Padera, Susan Chubinskaya, Accelerating Medicines Partnership: RA/SLE Network, Kevin Wei, Soumya Raychaudhuri, Lydia Lynch, D. Branch Moody, Michael B. Brenner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-11-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-024-52586-x
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