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Association of the inflammatory marker suPAR with chronic pruritus of unknown origin – data from the SOMA.PRU study

BackgroundChronic pruritus (CP) is a frequent and burdensome dermatological symptom that can occur both in skin conditions such as chronic atopic dermatitis (cAD) and as CP on non-lesional skin of unknown origin (CPUO). Mechanisms of pruritus chronicity remain poorly understood. In line with other p...

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Main Authors: Stefan M. Kahnert, Lara Jürgens, Leonie Dreher, Christian Schmidt-Lauber, Ansgar Koechel, Gina L. Frank, Tobias B. Huber, Meike Shedden-Mora, Sonja Ständer, Markus Ramm, Gudrun Schneider, Rupert Conrad
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-06-01
Series:Frontiers in Immunology
Subjects:
chronic inflammation
chronic pruritus
persistent somatic symptom
soluble urokinase plasminogen activator receptor
suPAR
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1804748/full
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