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An integrated proteomics and metabolomics analysis of methylglyoxal-induced neurotoxicity in a human neuroblastoma cell line

Abstract This study aimed to highlight the molecular and biochemical changes induced by methylglyoxal (MGO) exposure in SH-SY5Y human neuroblastoma cells, and to explore how these changes contribute to its neurotoxicity, utilizing an integrated proteomics and metabolomics approach. Using label-free...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Haomiao Wang, Sjef Boeren, Wouter Bakker, Ivonne M. C. M. Rietjens, Edoardo Saccenti, Liang Zheng
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2024-10-01
Цуврал:npj Science of Food
Онлайн хандалт:https://doi.org/10.1038/s41538-024-00328-0
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