Performance of somatic structural variant calling in lung cancer using Oxford Nanopore sequencing technology

Abstract Background Lung cancer is a heterogeneous disease and the primary cause of cancer-related mortality worldwide. Somatic mutations, including large structural variants, are important biomarkers in lung cancer for selecting targeted therapy. Genomic studies in lung cancer have been conducted u...

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Ngā kaituhi matua:	Lingchen Liu, Jia Zhang, Scott Wood, Felicity Newell, Conrad Leonard, Lambros T. Koufariotis, Katia Nones, Andrew J. Dalley, Haarika Chittoory, Farzad Bashirzadeh, Jung Hwa Son, Daniel Steinfort, Jonathan P. Williamson, Michael Bint, Carl Pahoff, Phan T. Nguyen, Scott Twaddell, David Arnold, Christopher Grainge, Peter T. Simpson, David Fielding, Nicola Waddell, John V. Pearson
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2024-09-01
Rangatū:	BMC Genomics
Ngā marau:	Long read sequencing Somatic structural variants detection Benchmarking long read approaches Small cell lung cancer
Urunga tuihono:	https://doi.org/10.1186/s12864-024-10792-3
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!

Performance of somatic structural variant calling in lung cancer using Oxford Nanopore sequencing technology

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