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Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles

Summary: High-density lipoproteins (HDLs) are a group of different subpopulations of sialylated particles that have an essential role in the reverse cholesterol transport (RCT) pathway. Importantly, changes in the protein and lipid composition of HDLs may lead to the formation of particles with redu...

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Hauptverfasser: Shahan Syed, Eija Nissilä, Hanna Ruhanen, Satoshi Fudo, Meztlli O. Gaytán, Sanna P. Sihvo, Martina B. Lorey, Jari Metso, Katariina Öörni, Samantha J. King, Oommen P. Oommen, Matti Jauhiainen, Seppo Meri, Reijo Käkelä, Karita Haapasalo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021-06-01
Schriftenreihe:iScience
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2589004221005034
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