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Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma

<p>Abstract</p> <p>Background</p> <p>We had previously demonstrated overexpression of fibroblast growth factor receptor-4 (FGFR4) in hepatocellular carcinoma (HCC). However, additional molecular mechanisms resulting in amplified FGFR4 signaling in HCC remain under-studied. Here, we studied the mecha...

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Principais autores: Poh Weijie, Wong Winnie, Ong Huimin, Aung Myat, Lim Seng, Chua Boon, Ho Han
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-03-01
coleção:Molecular Cancer
Assuntos:
FGFR4
Hepatocellular carcinoma
KLB
Liver stemness
Acesso em linha:http://www.molecular-cancer.com/content/11/1/14
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