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Limits of Classical Immune Response Models

We analyze parameter identifiability in a Marchuk-type immune-response model using longitudinal whole-blood transcriptomic signatures from the influenza challenge. Latent states are extracted from curated gene signatures derived from nine symptomatic and eight asymptomatic subjects. The governing de...

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Bibliografiske detaljer
Principais autores: Marina Bershadsky, Genady Kogan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-05-01
Serier:Computation
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Online adgang:https://www.mdpi.com/2079-3197/14/5/108
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