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Synthesis of Arginase Inhibitors: An Overview

Arginase (ARG) is a binuclear manganese-containing metalloenzyme that can convert L-arginine to L-ornithine and urea and plays a key role in the urea cycle. It also mediates different cellular functions and processes such as proliferation, senescence, apoptosis, autophagy, and inflammatory responses...

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Principais autores: Maria Cristina Molaro, Chiara Battisegola, Marica Erminia Schiano, Mariacristina Failla, Maria Grazia Rimoli, Loretta Lazzarato, Konstantin Chegaev, Federica Sodano
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-01-01
Serier:Pharmaceutics
Fag:
Arginase
Arginase inhibitors
synthetic protocols
Online adgang:https://www.mdpi.com/1999-4923/17/1/117
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