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Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: <it>ex vivo </it>effects and <it>in vivo </it>"traces" on the murine IAPE and human HERV-K elements

<p>Abstract</p> <p>Background</p> <p>APOBEC3 cytosine deaminases have been demonstrated to restrict infectivity of a series of retroviruses, with different efficiencies depending on the retrovirus. In addition, APOBEC3 proteins can severely restrict the intracellular transposition of a series of ret...

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Bibliografiske detaljer
Principais autores: Heidmann Odile, Ribet David, Priet Stéphane, Esnault Cécile, Heidmann Thierry
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2008-08-01
Serier:Retrovirology
Online adgang:http://www.retrovirology.com/content/5/1/75
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