Cell-Free Genic Extrachromosomal Circular DNA Profiles of DNase Knockouts Associated with Systemic Lupus Erythematosus and Relation with Common Fragile Sites

Cell-free extrachromosomal circular DNA (cf-eccDNA) has been proposed as a promising early biomarker for disease diagnosis, progression and drug response. Its established biomarker features are changes in the number and length distribution of cf-eccDNA. Another novel promising biomarker is a set of...

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Ngā kaituhi matua:	Daniela Gerovska, Patricia Fernández Moreno, Aitor Zabala, Marcos J. Araúzo-Bravo
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2023-12-01
Rangatū:	Biomedicines
Ngā marau:	extrachromosomal circular DNA (eccDNA) systemic lupus erythematosus (SLE) Dnase1 Dnase1l3 chromosomal fragile site (CFS) genome-wide association study (GWAS)
Urunga tuihono:	https://www.mdpi.com/2227-9059/12/1/80
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