Evaluating cell culture reliability in pediatric brain tumor primary cells through DNA methylation profiling

Abstract In vitro models of pediatric brain tumors (pBT) are instrumental for better understanding the mechanisms contributing to oncogenesis and testing new therapies; thus, ideally, they should recapitulate the original tumor. We applied DNA methylation (DNAm) and copy number variation (CNV) profi...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Lucia Pedace, Simone Pizzi, Luana Abballe, Maria Vinci, Celeste Antonacci, Sara Patrizi, Claudia Nardini, Francesca Del Bufalo, Sabrina Rossi, Giulia Pericoli, Francesca Gianno, Zein Mersini Besharat, Luca Tiberi, Angela Mastronuzzi, Elisabetta Ferretti, Marco Tartaglia, Franco Locatelli, Andrea Ciolfi, Evelina Miele
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-04-01
Colecção:	npj Precision Oncology
Acesso em linha:	https://doi.org/10.1038/s41698-024-00578-x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!