Genetic polymorphisms in interleukin-1β (rs1143634) and interleukin-8 (rs4073) are associated with survival after resection of intrahepatic cholangiocarcinoma

Abstract Intrahepatic cholangiocarcinoma (iCCA) is a rare, understudied primary hepatic malignancy with dismal outcomes. Aiming to identify prognostically relevant single-nucleotide polymorphisms, we analyzed 11 genetic variants with a role in tumor-promoting inflammation (VEGF, EGF, EGFR, IL-1B, IL...

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Principais autores:	Isabella Lurje, Nadine Therese Gaisa, Edgar Dahl, Ruth Knüchel, Pavel Strnad, Christian Trautwein, Frank Tacke, Ulf Peter Neumann, Zoltan Czigany, Georg Lurje
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2023-07-01
叢編:	Scientific Reports
在線閱讀:	https://doi.org/10.1038/s41598-023-39487-7
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