Quantitative transcriptomic and metabolic analyses reveal the roles of RpoS and Crp in the acid resistance system 1 in Escherichia coli

ABSTRACT Foodborne pathogens exploit acid resistance (AR) mechanisms to survive harsh environments, such as the stomach, increasing contamination risk. While the sigma factor RpoS and cyclic AMP receptor protein (Crp) are known mediators of AR, their systemic regulatory networks remain unclear. Here...

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Detalhes bibliográficos

Principais autores:	Wenbin Zhang, Liang Zhang, Jinxin Xu, Qinghua Huang, Ling Wang, Huohua Liu, Xin Chen, Zhonghai Sun, Qirui Zhou, Yujian Wu, Tianli Yu, Haihong Wang, Wei Lei, Yirong Sun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2026-07-01
coleção:	Microbiology Spectrum
Assuntos:	acid resistance RpoS Crp transcriptomics metabolic adaptation Escherichia coli
Acesso em linha:	https://journals.asm.org/doi/10.1128/spectrum.02063-25
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